Ventricular enlargement, neuropsychological status, and premorbid function in schizophrenia
نویسندگان
چکیده
منابع مشابه
Ventricular enlargement, neuropsychological status, and premorbid function in schizophrenia.
Ventricular enlargement is one of the most consistently documented neurobiological abnormalities in schizophrenia. The timing of the development of this abnormality in the course of schizophrenic illness and its relationship to neuropsychological dysfunction and premorbid adjustment is, however, unclear. To address these questions, we examined the relationship between ventricle-brain ratio (VBR...
متن کاملPremorbid adjustment in schizophrenia: implications for psychosocial and ventricular pathology.
Premorbid adjustment in schizophrenia is thought important (1) as a predictor of current pathology and course, and (2) as a psychosocial expression of brain pathology preceding psychosis. Its valid and reliable measurement, however, pose a major challenge. To address this issue we interviewed 12 chronic male schizophrenic veterans and their first degree relatives, plus 12 age and social class o...
متن کاملCorrelations of premorbid adjustment in schizophrenia with auditory event-related potential and neuropsychological abnormalities.
OBJECTIVE The authors examined the relationship between premorbid adjustment in schizophrenia and event-related potential data and neuropsychological data obtained after onset of the illness. METHOD They interviewed 13 male veterans with chronic schizophrenia, 12 normal comparison subjects, and their first-degree relatives and also obtained objective data from the patients' school records and...
متن کاملPopulation-based cohort studies on premorbid cognitive function in schizophrenia.
Many previous studies have found associations between poor cognitive function and schizophrenia. However, the majority of these studies used retrospective data, leading to the possibility of selection and recall biases. Retrospective studies are also unable to distinguish whether cognitive deficits exist prior to the onset of schizophrenia, suggesting that they are important in etiology, or fol...
متن کاملElaboration on premorbid intellectual performance in schizophrenia: premorbid intellectual decline and risk for schizophrenia.
CONTEXT Consistent evidence indicates that some, but not most, patients with schizophrenia have below-average intelligence years before they manifest psychosis. However, it is not clear whether this below-average premorbid intelligence is stable or progressive. OBJECTIVE To examine whether increased risk for schizophrenia is associated with declining intellectual performance from childhood th...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 1994
ISSN: 0006-3223
DOI: 10.1016/0006-3223(94)90098-1